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  Indian J Med Microbiol
 

Figure 3: Influence of Fu-Fang-Lu-Jiao-Shuang (FFLJS) on the histopathological change of ankle joint in collagen induced arthritis (CIA) mice. Fu-Fang-Lu-Jiao-Shuang inhibits the histological changes in the ankle joints of CIA mice. Paraffin sections of ankle joints were stained with H and E. (a) Nonimmunized mice showed normal articular cartilage, absence of damage in the synovium and open joint space. (b) CIA mice showed marked infiltration of inflammatory cells, narrow joint space with synovia hyperplasia. (c and d) CIA mice treated with FFLJS (125, 500 mg/kg) and (e) dexamethasone (3 mg/kg) showed less inflammatory cells infiltration, well preserved joint spaces and minimal synovia hyperplasia. (a) Infiltration of inflammatory cells; (b) cartilage hyperplasia and close articular cavity

Figure 3: Influence of Fu-Fang-Lu-Jiao-Shuang (FFLJS) on the histopathological change of ankle joint in collagen induced arthritis (CIA) mice. Fu-Fang-Lu-Jiao-Shuang inhibits the histological changes in the ankle joints of CIA mice. Paraffin sections of ankle joints were stained with H and E. (a) Nonimmunized mice showed normal articular cartilage, absence of damage in the synovium and open joint space. (b) CIA mice showed marked infiltration of inflammatory cells, narrow joint space with synovia hyperplasia. (c and d) CIA mice treated with FFLJS (125, 500 mg/kg) and (e) dexamethasone (3 mg/kg) showed less inflammatory cells infiltration, well preserved joint spaces and minimal synovia hyperplasia. (a) Infiltration of inflammatory cells; (b) cartilage hyperplasia and close articular cavity