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  Indian J Med Microbiol
 

Figure 1: The effect of cryptotanshinone (CT) on cell viability and apoptosis in MC-3 cells. (a) Chemical structure of CT. MC-3 cells were treated with 2, 4, or 8 ƒÊM of CT for 24 h. Cell viability was determined using a trypan blue exclusion assay. (b) The apoptotic effect of CT was determined by Western blot analysis using the antibodies against cleaved poly ADP ribose polymerase and cleaved caspase 3 (c) and 4'-6-diamidino-2-phenylindole staining. (d) Results are expressed as means ± standard deviation for triplicate experiments and significance ( P < 0.05) compared with dimethyl sulfoxide-treated cells is given (*)

Figure 1: The effect of cryptotanshinone (CT) on cell viability and apoptosis in MC-3 cells. (a) Chemical structure of CT. MC-3 cells were treated with 2, 4, or 8 ƒÊM of CT for 24 h. Cell viability was determined using a trypan blue exclusion assay. (b) The apoptotic effect of CT was determined by Western blot analysis using the antibodies against cleaved poly ADP ribose polymerase and cleaved caspase 3 (c) and 4'-6-diamidino-2-phenylindole staining. (d) Results are expressed as means ± standard deviation for triplicate experiments and significance ( <i>P</i> < 0.05) compared with dimethyl sulfoxide-treated cells is given (*)