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  Indian J Med Microbiol
 

Figure 10: In vivo antitumor activity of Octacosane and Triacontane. Six-week-old male C57BL/6 mice were injected subcutaneously with 5×104 B16F10-Nex2 tumor cells. Peritumor treatment started 24 h after tumor inoculation. Five animals per group were used. Alkanes (500 μg) were injected in 100 μl of 5% DMSO in PBS. Daily doses were given during all treatment period. Tumor size was measured seven times a week with a caliper until the tumor volume reached a maximum of 3000mm3 when the animals were sacrificed. The control group was treated with vehicle PBS/DMSO 5%. *P<0.05, indicates significant differences between groups

Figure 10: <i>In vivo</i> antitumor activity of Octacosane and Triacontane. Six-week-old male C57BL/6 mice were injected subcutaneously with 5×104 B16F10-Nex2 tumor cells. Peritumor treatment started 24 h after tumor inoculation. Five animals per group were used. Alkanes (500 μg) were injected in 100 μl of 5% DMSO in PBS. Daily doses were given during all treatment period. Tumor size was measured seven times a week with a caliper until the tumor volume reached a maximum of 3000mm3 when the animals were sacrificed. The control group was treated with vehicle PBS/DMSO 5%. *<i>P</i><0.05, indicates significant differences between groups