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  Indian J Med Microbiol
 

Figure 3: The K562 cells were incubated for 48 h without lycopene or with lycopene in the free and encapsulated forms (100 μg/ml) (a) and nuclear morphological changes observed under the fluorescent microscope after staining with hoechst 33342. As compared to control cells (b) fragmented or condensed nuclei indicative of apoptosis could be observed in the lycopene-treated as arrows indicated. The rate of apoptotic K562 cells after treatment with the lycopene in the free (c) and encapsulated (d) forms are presented in the Figure 3. Data represent as mean ± standard deviation from three independent experiments (*P < 0.05 and **P < 0.001)

Figure 3: The K562 cells were incubated for 48 h without lycopene or with lycopene in the free and encapsulated forms (100 μg/ml) (a) and nuclear morphological changes observed under the fluorescent microscope after staining with hoechst 33342. As compared to control cells (b) fragmented or condensed nuclei indicative of apoptosis could be observed in the lycopene-treated as arrows indicated. The rate of apoptotic K562 cells after treatment with the lycopene in the free (c) and encapsulated (d) forms are presented in the Figure 3. Data represent as mean ± standard deviation from three independent experiments (*<i>P</i> < 0.05 and **<i>P</i> < 0.001)