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  Indian J Med Microbiol
 

Figure 2: Photomicrographs of the rat colon (H and E, ×100) (a) normal saline + carboxymethyl cellulose (CMC) showing relatively normal and clear structure with intact mucosa and sub mucosa (b) 2,4,6-trinitrobenzene sulfonic acid (TNBS) + CMC showing crypt destruction with severe cryptitis (blue arrow), ulceration with eroded mucosa (brown arrow), lymphoplasmacytic infiltrate (white arrow) and transmural inflammation (Yellow arrow) (c) TNBS + AME showing regenerative mucosa with mild crypt distortion and mild lymphoplasmacytic infiltrate in the lamina propria with edematous submucosa and (d) TNBS + SS showing intact mucosa with minimal lymphoplasmacytic infiltrate in the lamina propria (M = Mucosa; SM = Submucosa; LP = Lamina propria; MM = Muscularis mucosa; ME = Muscularis externa)

Figure 2: Photomicrographs of the rat colon (H and E, ×100) (a) normal saline + carboxymethyl cellulose (CMC) showing relatively normal and clear structure with intact mucosa and sub mucosa (b) 2,4,6-trinitrobenzene sulfonic acid (TNBS) + CMC showing crypt destruction with severe cryptitis (blue arrow), ulceration with eroded mucosa (brown arrow), lymphoplasmacytic infiltrate (white arrow) and transmural inflammation (Yellow arrow) (c) TNBS + <i>AME</i> showing regenerative mucosa with mild crypt distortion and mild lymphoplasmacytic infiltrate in the lamina propria with edematous submucosa and (d) TNBS + SS showing intact mucosa with minimal lymphoplasmacytic infiltrate in the lamina propria (M = Mucosa; SM = Submucosa; LP = Lamina propria; MM = Muscularis mucosa; ME = Muscularis externa)