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  Indian J Med Microbiol
 

Figure 1: Chronograms showing circadian patterns for mouse body temperature at baseline (B) and 1 hour later after oral placebo (P) at six treatment times [in hours after lights on (HALO, h)]. 4-hour means ± SE from mice studied in LD 12:12 (6 mice/timepoint, 36 total) are shown with best-fitting 24-hour cosine. For time-effect, P-values from fit of a 24-hour cosine were 0.013 for B and 0.017 for P. No significant differences between B versus P were found for 24-hour mean (mesor) (35.58 vs. 35.69°C), amplitude (0.56 vs. 0.63°C), or acrophase (15:31 h vs. 15:40 h), allowing averaging for further comparison following Acn treatments. Dark bar = 12-hour dark/activity span

Figure 1: Chronograms showing circadian patterns for mouse body temperature at baseline (B) and 1 hour later after oral placebo (P) at six treatment times [in hours after lights on (HALO, h)]. 4-hour means ± SE from mice studied in LD 12:12 (6 mice/timepoint, 36 total) are shown with best-fitting 24-hour cosine. For time-effect, <i>P</i>-values from fit of a 24-hour cosine were 0.013 for B and 0.017 for P. No significant differences between B versus P were found for 24-hour mean (mesor) (35.58 vs. 35.69°C), amplitude (0.56 vs. 0.63°C), or acrophase (15:31 h vs. 15:40 h), allowing averaging for further comparison following <i>Acn</i> treatments. Dark bar = 12-hour dark/activity span