Pharmacognosy Magazine

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 10  |  Issue : 37  |  Page : 40--46

Aliphatic and eudesmalolide esters extracted from the roots of Inula racemosa Hook


Maria Khan1, SR Mir1, Abuzar Ali1, Mohammad Yusuf2, Mohammed Ali1 
1 Department of Pharmacognosy and Phytochemistry, Phytochemistry Research Laboratory, Jamia Hamdard, New Delhi, India
2 Department of Pharmaceutical Chemistry, Jamia Hamdard, New Delhi, India

Correspondence Address:
Mohammed Ali
Department of Pharmacognosy and Phytochemistry, Jamia Hamdard, New Delhi - 110 062
India

Background: Phytochemical investigation of hydroalcoholic extract of the root of Inula racemosa Hook. Materials and Methods: Open silica gel column chromatographic techniques with different solvent systems was used for isolation of aliphatic and eudesmalolide esters from hydroalcoholic extract of the root of Inula racemosa. The structure elucidation of the compounds was done on the basis of spectral data analysis, chemical reactions and comparision with literature data. Results: Phytochemical investigation of the hydroalcoholic extract of the root of Inula racemosa Hook. f. led to the isolation of (5z, 13z)-n-decanyl-n-docos-5, 13-dienoate, a new fatty acid ester, two new sesquiterpenic ester identified as 15-[(13z, 18SQz, 20SQz)-n-tricos-13, 18, 20-trienyl]-eudesmal-4 (11), 6, 12 (13)-trien-8,14-olide-15-oate and 15- [(16SQz), (21SQz)-n- tetracos-16SQ, 21SQ- dienyl]-eudesmal-4 (11) 6, 12 (13)-trien-8, 14-olide-15-oate, two new eudesmanolide ester i.e. 15-[(16z)-n-monadec-16SQ- enyl]-eudesmal-4 (11) 6, 12 (13)-trien-8,14-olide-15-oate and 15-[(16SQz)-n-tetracos-16SQ- enyl]-endesmal-4 (11), 6, 12 (13)-trien-8,14-olide-15-oate along with the known compound n-Hexadecanyl n-docosanoate. Conclusion: Five new phytoconstituents were identified along with one known compound as aliphatic and eudesmalolide esters from the hydroalcoholic extract of the root of Inula racemosa, as mentioned above.


How to cite this article:
Khan M, Mir S R, Ali A, Yusuf M, Ali M. Aliphatic and eudesmalolide esters extracted from the roots of Inula racemosa Hook.Phcog Mag 2014;10:40-46


How to cite this URL:
Khan M, Mir S R, Ali A, Yusuf M, Ali M. Aliphatic and eudesmalolide esters extracted from the roots of Inula racemosa Hook. Phcog Mag [serial online] 2014 [cited 2020 Apr 7 ];10:40-46
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2014;volume=10;issue=37;spage=40;epage=46;aulast=Khan;type=0