Pharmacognosy Magazine

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 10  |  Issue : 37  |  Page : 164--170

Chemical composition of the volatile oil from Zanthoxylum avicennae and antimicrobial activities and cytotoxicity


Yin Lin1, Wei Han3, Wei-chen Ge2, Ke Yuan2 
1 The Nurturing Station for the State Key Laboratory of Subtropical Silviculture, Zhejiang Agriculture and Forestry University, Lin'an; School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
2 The Nurturing Station for the State Key Laboratory of Subtropical Silviculture, Zhejiang Agriculture and Forestry University, Lin'an, China

Correspondence Address:
Ke Yuan
The Nurturing Station for the State Key Laboratory of Subtropical Silviculture, Zhejiang Agriculture and Forestry University, Lin«SQ»an, 311300
China

Background: Through literature retrieval, there has been no report on the research of the chemical components in Zanthoxylum avicennae (Lam.) DC. This paper extracted and determined the chemical components of the volatile oil in Z. avicennae, and at the same time, measured and evaluated the bioactivity of the volatile oil in Z. avicennae. Materials and Methods: We extract the volatile oil in Z. avicennae by steam distillation method, determined the chemical composition of the volatile oil by GC-MS coupling technique, and adopt the peak area normalization method to measured the relative percentage of each chemical composition in the volatile oil. Meanwhile, we use the Lethal-to-prawn larva bioactivity experiment to screen the cytotoxicity activities of the volatile oil in Z. avicennae, and using the slanting test-tube experiment to determine and evaluate its antibacterial activities in vitro for the eight kinds of plant pathogenic fungi in the volatile oil of the Z. avicennae. Results: The results show that 68 kinds of compounds are determined from the volatile oil of Z. avicennae. The determined part takes up 97.89% of the total peak area. The main ingredients in the volatile oil of Z. avicennae are sesquiterpenoids and monoterpene. The test results show that the volatile oil in Z. avicennae has strong antibacterial activities and cytotoxicity, with the strongest antibacterial activity against the Rhizoctonia solani AG1-1A. Conclusion: This research results will provide reference data for understanding the chemical composition of the volatile oil in the aromatic plant of Z. avicennae and its bioactivity, and for its further development and application.


How to cite this article:
Lin Y, Han W, Ge Wc, Yuan K. Chemical composition of the volatile oil from Zanthoxylum avicennae and antimicrobial activities and cytotoxicity.Phcog Mag 2014;10:164-170


How to cite this URL:
Lin Y, Han W, Ge Wc, Yuan K. Chemical composition of the volatile oil from Zanthoxylum avicennae and antimicrobial activities and cytotoxicity. Phcog Mag [serial online] 2014 [cited 2019 Aug 25 ];10:164-170
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2014;volume=10;issue=37;spage=164;epage=170;aulast=Lin;type=0