Pharmacognosy Magazine

ORIGINAL ARTICLE
Year
: 2010  |  Volume : 6  |  Issue : 22  |  Page : 142--144

Anticholinesterase activities of cold and hot aqueous extracts of F. racemosa stem bark


Faiyaz Ahmed, Asna Urooj 
 Department of Studies in Food Science and Nutrition, University of Mysore, Manasagangotri, Mysore - 570 006, India

Correspondence Address:
Faiyaz Ahmed
Department of Studies in Food Science and Nutrition, University of Mysore, Manasagangotri, Mysore - 570 006
India

The present study evaluated the anticholinesterase activity of cold and hot aqueous extracts of Ficus racemosa stem bark against rat brain acetylcholinesterase in vitro. Both the cold aqueous extract (FRC) and the hot aqueous extract (FRH) exhibited a dose dependent inhibition of rat brain acetylcholinesterase. FRH showed significantly higher ( p ≤ 0.001) cholinesterase inhibitory activity compared to FRC; however, both the extracts did not show 50% inhibition of AChE at the doses tested (200-1000 μg ml -1 ). The IC 50 values of 1813 and 1331 μg ml -1 were deduced for FRC and FRH, respectively (calculated by extrapolation using Boltzmann«SQ»s dose response analysis).


How to cite this article:
Ahmed F, Urooj A. Anticholinesterase activities of cold and hot aqueous extracts of F. racemosa stem bark.Phcog Mag 2010;6:142-144


How to cite this URL:
Ahmed F, Urooj A. Anticholinesterase activities of cold and hot aqueous extracts of F. racemosa stem bark. Phcog Mag [serial online] 2010 [cited 2020 Mar 29 ];6:142-144
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2010;volume=6;issue=22;spage=142;epage=144;aulast=Ahmed;type=0