Pharmacognosy Magazine

RESEARCH ARTICLE
Year
: 2009  |  Volume : 5  |  Issue : 18  |  Page : 134--138

The Postprandial Hypoglycemic Activity of Fenugreek Seed and Seeds«SQ» Extract in Type 2 Diabetics: A Pilot Study


Hiba A Bawadi1, Sofyan N Maghaydah2, Rabab F Tayyem3, Reema F Tayyem3 
1 Department of Nutrition and Food Technology, Jordan University of Science and Technology, Jordan
2 Faculty of Pharmacy, The University of Jordan, Jordan
3 Department of Clinical Nutrition and Dietetics, Faculty of Allied Health Sciences, The Hashemite University, Jordan

Correspondence Address:
Rabab F Tayyem
Department of Clinical Nutrition and Dietetics, Faculty of Allied Health Sciences, The Hashemite University
Jordan

Trigonella foenum-groecum L. is directly related to the traditional use. Trigonella foenum-graecum L, have been reported to be beneficial for treating type 2 diabetes (T2D). The study was conducted to investigate the postprandial hypoglycemic effect of fenugreek seeds on patients with T2D. Pretest - posttest control group design was used to test the hypothesis that fenugreek may have a hypoglycemic effect on blood sugar. One hundred sixty-­six D2T patients were assigned into three groups: FGO (control group: placebo drink), FG2.5 (2.5g of fenugreek), and FG5 (5g of fenugreek). Participants were instructed to drink the extract and chew the seeds. Postprandial plasma glucose level was measured before and 2-hours after the administration of the treatment. Accounting for gender, age, education, physical activity, body mass index, glycemic control, and medication, patients in FG5 group showed the greatest decrease in postprandial glucose with a pretest-posttest difference (D) of - 41 ± 6.1 mg/dl. Two-hour plasma glucose dropped for patients in FG2.5, however, the drop was not statistically different from that noticed in the placebo group (D = - 24.8 ± 4.9 mg/dl vs. - 9.8 ± 2.2 mg/dl respectively). Fenugreek seeds appear to have a significant hypoglycemic activity in T2D patients.


How to cite this article:
Bawadi HA, Maghaydah SN, Tayyem RF, Tayyem RF. The Postprandial Hypoglycemic Activity of Fenugreek Seed and Seeds' Extract in Type 2 Diabetics: A Pilot Study.Phcog Mag 2009;5:134-138


How to cite this URL:
Bawadi HA, Maghaydah SN, Tayyem RF, Tayyem RF. The Postprandial Hypoglycemic Activity of Fenugreek Seed and Seeds' Extract in Type 2 Diabetics: A Pilot Study. Phcog Mag [serial online] 2009 [cited 2020 Aug 12 ];5:134-138
Available from: http://www.phcog.com/article.asp?issn=0973-1296;year=2009;volume=5;issue=18;spage=134;epage=138;aulast=Bawadi;type=0