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ORIGINAL ARTICLE
Year : 2018  |  Volume : 14  |  Issue : 58  |  Page : 525-527

Secondary metabolites from Sibiraea angustata


1 Department of Biotechnology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China
2 Department of Biotechnology, School of Life Science and Technology; Center For Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China

Correspondence Address:
Guang-Bo Xie
Department of Biotechnology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/pm.pm_390_17

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Background: Sibiraea angustata was used as folk medicine in Tibetan-inhabited area of Hengduan Mountains, China. Objective: The secondary metabolites from the leaves and twigs of S. angustata were studied. Materials and Methods: The compounds were isolated and purified using silica gel and Sephadex LH-20 column chromatography. Their structures were identified by spectra analysis. Results: Eight known compounds, including 2 monoterpenoids and 3 triterpenoids, were isolated and identified from S. angustata. Conclusions: Four compounds were isolated from this plant for the first time, and the 13C-nuclear magnetic resonance spectra data and absolute configuration of dihydroneroloxide were given for the first time. Abbreviations used: NMR: Nuclear magnetic resonance; TMS: Tetramethylsilane; ECD: Electronic circular dichroism; CC: Column chromatography; TLC: Thin-layer chromatography; DFT: Density functional theory; TDDFT: Time-dependent density functional theory; PCM: Polarizable continuum model.


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