Home | About PM | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Pharmacognosy Magazine
Search Article 
  
Advanced search 
 
ORIGINAL ARTICLE
Year : 2015  |  Volume : 11  |  Issue : 44  |  Page : 625-633

In vitro antimicrobial activity of traditional plant used in mestizo shamanism from the Peruvian amazon in case of infectious diseases


1 Division of Natural Products Chemistry, Laboratoire Régional de Recherche en Agro-alimentaire et Biotechnologie: Institut Charles Viollette, Lille, France
2 Division of Anthropology, Ecole pratique des hautes études, Laboratoire d'anthropologie sociale, 75005 Paris, Sorbonne, France
3 Division of Natural Products Chemistry, Laboratorio de Investigación de Productos Naturales Antiparasitarios de la Amazonia, Universidad Nacional de la Amazonía Peruana, AA.HH., Nuevo San Lorenzo, Iquitos, Peru
4 Division of Bacteriology, Laboratoire de Bactériologie, Faculté des Sciences Pharmaceutiques et Biologiques, Université Lille Nord de France (Lille 2), F-59006 Lille Cedex, France

Correspondence Address:
Vincent Roumy
Division of Natural Products Chemistry, Laboratoire Régional de Recherche en Agro-alimentaire et Biotechnologie: Institut Charles Viollette, Lille
France
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1296.172975

Rights and Permissions

Context: Our survey was performed near Iquitos (Peruvian Amazon) and its surroundings and leads us to consider Mestizo ethnomedical practices. The plant species reported here are traditionally used for ailments related to microbial infections. Inhabitants of various ethnic origins were interviewed, and 52 selected plants extracts were evaluated for their antimicrobial properties against a panel of 36 sensitive and multi-resistant bacteria or yeast. The study aimed at providing information on antimicrobial plant extract activities and the ethnomedical context of Mestizo riverine populations from Loreto (Peru). Material and Method: The minimum inhibitory concentrations (MICs) of the plant crude extracts were carried out using the agar dilution method and ranged between 0.075 and 5.0 mg/ml. Results: Of the 40 plants analyzed, 9 species showed MIC ≤0.3 mg/ml (Anacardium occidentale, Couroupita guianensis, Croton lechleri, Davilla rugosa, Erythrina amazonica, Jacaranda copaia subsp. Spectabilis, Oenocarpus bataua, Peperomia macrostachya, and Phyllanthus urinaria) for one or several of the 36 microorganisms and only 6 drug extracts were inactive. Among the 40 plants, 13 were evaluated for the first time for an antibacterial activity. Conclusion: This evaluation of the antimicrobial activity of 40 plants using an approved standard methodology allowed comparing those activities against various microbes to establish antimicrobial spectra of standardized plant extracts, and give support to the traditional use of these plants. It may also help discovering new chemical classes of antimicrobial agents that could serve against multi-resistant bacteria.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1914    
    Printed44    
    Emailed0    
    PDF Downloaded23    
    Comments [Add]    
    Cited by others 1    

Recommend this journal