Home | About PM | Editorial board | Search | Ahead of print | Current Issue | Archives | Instructions | Subscribe | Advertise | Contact us |  Login 
Pharmacognosy Magazine
Search Article 
  
Advanced search 
 
ORIGINAL ARTICLE
Year : 2015  |  Volume : 11  |  Issue : 43  |  Page : 657-664

Quantification of maltol in Korean ginseng ( Panax ginseng) products by high-performance liquid chromatography-diode array detector


Ginseng Research Center, Food Research Institute, Seongnam, Gyeonggi 463-746, Korea

Correspondence Address:
Chang-Won Cho
Ginseng Research Center, Food Research Institute, Seongnam, Gyeonggi 463-746
Korea
Login to access the Email id

Source of Support: This work was supported by research grants from the Korea Food Research Institute (Project No. E0132202), Conflict of Interest: None declared.


DOI: 10.4103/0973-1296.160452

Rights and Permissions

Background: Maltol, as a type of phenolic compounds, is produced by the browning reaction during the high temperature treatment of ginseng. Thus, maltol can be used as a marker for the quality control of various ginseng products manufactured by high temperature treatment including red ginseng. For the quantification of maltol in Korean ginseng products, an effective high performance liquid chromatography diode array detector (HPLC DAD) method was developed. Materials and Methods: The HPLC DAD method for maltol quantification coupled with a liquid liquid extraction (LLE) method was developed and validated in terms of linearity, precision, and accuracy. An HPLC separation was performed on a C18 column. Results: The LLE methods and HPLC running conditions for maltol quantification were optimized. The calibration curve of the maltol exhibited good linearity (R2 = 1.00). The limit of detection value of maltol was 0.26 μg/mL, and the limit of quantification value was 0.79 μg/mL. The relative standard deviations (RSDs) of the data of the intra and inter day experiments were <1.27% and 0.61%, respectively. The results of the recovery test were 101.35–101.75% with an RSD value of 0.21–1.65%. The developed method was applied successfully to quantify the maltol in three ginseng products manufactured by different methods. Conclusion: The results of validation demonstrated that the proposed HPLC DAD method was useful for the quantification of maltol in various ginseng products.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1557    
    Printed32    
    Emailed0    
    PDF Downloaded17    
    Comments [Add]    
    Cited by others 1    

Recommend this journal