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ORIGINAL ARTICLE
Year : 2013  |  Volume : 9  |  Issue : 33  |  Page : 67-71

The high-performance liquid chromatographic fingerprints study of Awei capsules


The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China

Correspondence Address:
Jie Xue
Xinjiang Medical University, Urumqi-830011, Xinjiang
China
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Source of Support: This research was supported by National Natural Science Foundation of China(No.81060332). We also thank Mr. Mingxin Zhou for his assistance and support during the course of this study., Conflict of Interest: None


DOI: 10.4103/0973-1296.108143

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Background: Awei Capusules are Hospital preparation for Hyperlipidemia. It was composed by Awei, Magnoliae Officinalis and Polygonum Bistoral etc. Manufacture and quality standard of Awei Capusules had been studied. Results of animal pharmacodynamic and clinical study all displayed that Awei Capusules can reduce serum levels of TC, TG, LDL-C, increases HDL-C/TC. It was safe. It could improve hemorrheology and vessel function of blood stasis animal. On the basis of these, we studied on fingerprint of Awei capsule. Materials and Methods: The gradient elution method was used for analyzing samples on HPLC. Fingerprint similarity calculation software was used for data analysis. Results: We got a good separation of Awei Capusules peaks. There were 15 peaks in fingerprint of Awei capusles. Gallic acid, magnolol and honokiol were identified. Conclusion: HPLC fingerprinting of Awei Capusules can provide to reference. It can control preparations quality of Awei Capusules.


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