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ORIGINAL ARTICLE
Year : 2012  |  Volume : 8  |  Issue : 29  |  Page : 37-41

Comparative study of rosmarinic acid content in some plants of Labiatae family


1 Department of Research and Development, Food and Drug Laboratory Research Center and Food and Drug Control Laboratories, MOH and ME, Tehran, Iran
2 Traditional Medicine and Materia Medica Research Center; Department of Traditional Pharmacy, Faculty of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3 Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran

Correspondence Address:
Homa Hajimehdipoor
Traditional Medicine and Materia Medica Research Center and Department of Traditional Pharmacy, Faculty of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran
Iran
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Source of Support: Tehran University of Medical Sciences and Health Services (Grant No. 87-04-56-7508), Conflict of Interest: None


DOI: 10.4103/0973-1296.93316

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Background: Plants of Labiatae are used in traditional medicine and phytotherapy. Rosmarinic acid (RA) is a phenolic compound which is found in many genus of Labiatae and exhibits important biological activities. Materials and Methods: In this investigation, RA contents of 29 species of Labiatae named Salvia officinalis, Salvia limbata, Salvia virgata, Salvia hypoleuca, Salvia macrosiphon, Salvia choloroleuca, Melissa officinalis, Origanum vulgare, Lavandula angustifolia, Rosmarinus officinalis, Thymus daenensis, Thymus citriodorous, Thymus pubescens, Thymus vulgaris, Zataria multiflora, Mentha piperita, Mentha pulegium, Mentha longifolia, Mentha spicata, Mentha aquatica, Mentha crispa, Perovskia artemisoides, Zhumeria majdae, Satureja hortensis, Satureja khuzistanica, Satureja bachtiarica, Satureja atropatana, Satureja mutica and Satureja macrantha were determined by using high-performance liquid chromatographic method. Results: The results showed that RA content in different species of Labiatae was 0.0-58.5 mg g -1 of dried plants. The highest amount of RA was found in Mentha species especially M. spicata. Conclusion: M. spicata can be considered as a new source of rosmarinic acid .


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