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ORIGINAL ARTICLE
Year : 2010  |  Volume : 6  |  Issue : 22  |  Page : 132-134

Comparative analgesic effect of Ligusticum chuanxiong pieces and its products in mice


School of Pharmacy, Shandong University of Traditional Chinese Medicine, 250355 Jinan, China

Correspondence Address:
Demin GAO
School of Pharmacy, Shandong University of Traditional Chinese Medicine, 250355 Jinan
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0973-1296.62902

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The present study was undertaken with the objective of finding out the comparative analgesic effect of Ligusticum chuanxiong (LC) pieces decoction, LC formula granule decoction, liquored LC pieces decoction and liquored LC formula granule decoction. The analgesic effects were analyzed using the hot plate and acetic-induced writhing test in mice, and antidysmenorrheic effect was observed with primary dysmenorrhea model. The results showed that four kinds of LC decoction had definite effect in delaying incubation period and decreasing the writhing frequency within 30 min. They also effectively relieved dysmenorrhea. Moreover, liquored LC had better analgesic effect than crude LC in four decoctions.


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